Sumoylationpathway

由 CM Brackett 著作 · 2021 · 被引用 13 次 — The enzymatic pathway of SUMOylation is very similar to ubiquitinylation and involves an activating enzyme, a conjugating enzyme, ligases, and deconjugating ...

由 L Gong 著作 · 2017 · 被引用 21 次 — Sumoylation is a covalent protein posttranslational modification that conjugates the small ubiquitin-like peptide SUMO to substrate.

由 TK Sajeev 著作 · 2021 · 被引用 18 次 — Unlike ubiquitination, SUMOylation alters localization, interactions, functions, or stability of target proteins. This review provides an ...

由 G Joshi 著作 · 2021 · 被引用 18 次 — SUMOylation of IRF3 and IRF7 acts as a negative regulator of the type-I interferon pathway leading to reduced interferon production. SUMO- ...

由 KA Wilkinson 著作 · 被引用 742 次 — The post-translational modification SUMOylation is a major regulator of protein function that plays an important role in a wide range of cellular processes.

由 L Wang 著作 · 2021 · 被引用 6 次 — Increasing evidence has shown that SUMO enzymes participate in cell proliferation, cell division, chromosomal instability, apoptosis and stress-response in ...

由 JR Gareau 著作 · 2010 · 被引用 1200 次 — The SUMO pathway ... The process of activating and attaching a SUMO to substrates results in the formation of an isopeptide bond between the carboxy-terminal ...